About Hemostemix

About Hemostemix

Hemostemix Inc. is a clinical-stage regenerative medicine company advancing investigational autologous cell therapy programs for vascular and ischemic disease.

 Clinical-Stage Biotechnology Company

Founded in 2003, Hemostemix is focused on the development and clinical evaluation of autologous angiogenic cell therapies derived from a patient’s own blood.
 
The company’s lead investigational candidate, ACP-01 (Angiogenic Cell Precursors), has been evaluated in Phase I and Phase II clinical studies across multiple ischemic and cardiovascular indications.
 
Hemostemix operates at the intersection of clinical research, cellular biology, and manufacturing infrastructure, with a long-term commitment to structured development and regulatory alignment.


 

Roger Bergersen

 Our Founder’s Story

Roger Bergersen was the principal founder of TheraVitae Inc., which later became Hemostemix Inc.

Roger was a key figure in developing and championing our autologous stem cell therapy, originally known as VesCell™ and now referred to as ACP-01 (Angiogenic Cell Precursors).

Bergersen’s involvement stemmed from his personal experience. In 2005, facing critical heart disease, he traveled to Bangkok, Thailand for experimental treatment. That treatment involved an early version of our autologous stem cell product ACP-01 derived from his own blood. The treatment involved harvesting his blood, processing it to isolate angiogenic precursor cells, multiplying them, then injecting them into the affected area to promote new blood vessel formation (angiogenesis) and tissue repair.

He claimed that this compassionate-use or early treatment saved his life and so dramatically improved his condition that he founded the company to make the technology more widely available.

Since that time, Hemostemix has conducted multiple clinical studies on ACP-01 for conditions including critical limb ischemia (CLI), ischemic cardiomyopathy, angina, vascular dementia, and other ischemic diseases. Our research continues as we move toward new clinical trials.

ACP-01 has been administered to hundreds of patients across trials and compassionate programs, with published results showing safety, ulcer healing, pain resolution, and sustained benefits in some cases up to 4.5+ years, and longer in individual compassionate cases such as one patient highlighted at 13 years and another at 17+ years post-treatment.  His experience became the foundation for two decades of structured clinical research aimed at understanding whether that outcome could be studied, replicated, and made available to others. 

Bergersen received his initial treatment in 2005. He passed away in his sleep on February 27, 2020, having lived another 15 years following his procedure. He remained deeply passionate about ACP-01 and dedicated his efforts to advancing the technology for others facing serious ischemic disease.

Hemostemix announced his passing in March 2020, highlighting his foundational role and his commitment to expanding research in autologous angiogenic therapies.


 

 Our Founder’s Story

Roger Bergersen was the principal founder of TheraVitae Inc., which later became Hemostemix Inc.

Roger was a key figure in developing and championing our autologous stem cell therapy, originally known as VesCell™ and now referred to as ACP-01 (Angiogenic Cell Precursors).

Bergersen’s involvement stemmed from his personal experience. In 2005, facing critical heart disease, he traveled to Bangkok, Thailand for experimental treatment. That treatment involved an early version of our autologous stem cell product ACP-01 derived from his own blood. The treatment involved harvesting his blood, processing it to isolate angiogenic precursor cells, multiplying them, then injecting them into the affected area to promote new blood vessel formation (angiogenesis) and tissue repair.

He claimed that this compassionate-use or early treatment saved his life and so dramatically improved his condition that he founded the company to make the technology more widely available.

Since that time, Hemostemix has conducted multiple clinical studies on ACP-01 for conditions including critical limb ischemia (CLI), ischemic cardiomyopathy, angina, vascular dementia, and other ischemic diseases. Our research continues as we move toward new clinical trials.

ACP-01 has been administered to hundreds of patients across trials and compassionate programs, with published results showing safety, ulcer healing, pain resolution, and sustained benefits in some cases up to 4.5+ years, and longer in individual compassionate cases such as one patient highlighted at 13 years and another at 17+ years post-treatment.  His experience became the foundation for two decades of structured clinical research aimed at understanding whether that outcome could be studied, replicated, and made available to others. 

Bergersen received his initial treatment in 2005. He passed away in his sleep on February 27, 2020, having lived another 15 years following his procedure. He remained deeply passionate about ACP-01 and dedicated his efforts to advancing the technology for others facing serious ischemic disease.

Hemostemix announced his passing in March 2020, highlighting his foundational role and his commitment to expanding research in autologous angiogenic therapies.


 

Clinical Development and Research

Hemostemix has conducted multiple Phase I and Phase II clinical investigations evaluating ACP-01 across ischemic and cardiovascular indications.

Clinical programs have included:

Chronic Limb Threatening Ischemia
Peripheral Arterial Disease
Ischemic Cardiomyopathy
Heart Failure
Angina
Vascular Dementia
Non-healing Wounds
Chronic Pain

Published peer-reviewed findings have evaluated safety and functional outcomes within defined patient populations.

ACP-01 remains investigational in all indications and continues to be evaluated through structured clinical programs.

 

Clinical Development and Research

Hemostemix has conducted multiple Phase I and Phase II clinical investigations evaluating ACP-01 across ischemic and cardiovascular indications.

Clinical programs have included:


  • Chronic Limb Threatening Ischemia 
  • Peripheral Arterial Disease 
  • Ischemic Cardiomyopathy
  • Heart Failure
  • Angina
  • Vascular Dementia
  • Non-healing Wounds
  • Chronic Pain

  

Published peer-reviewed findings have evaluated safety and functional outcomes within defined patient populations.

ACP-01 remains investigational in all indications and continues to be evaluated through structured clinical programs.

 

 Commitment to Responsible Development 

Hemostemix is committed to:

Ethical clinical research
Transparent communication with investors and stakeholders
Compliance with applicable regulatory frameworks
Continued advancement of investigational therapies through structured scientific evaluation

 

 Leadership and Governance 

 

Hemostemix is led by a management team and board with experience in biotechnology, clinical research, corporate development, and operational strategy.

 

Our Leadership Team

Hemostemix-Tom
Thomas A. Smeenk, BA

President & CEO. Co-Founder

Thomas leads Hemostemix Inc. (TSXV: HEM | OTCQB: HMTXF), a clinical-stage biotechnology company revolutionizing regenerative medicine through autologous stem cell therapy.

For over two decades, Thomas has led Hemostemix from a visionary startup, recognized as a World Economic Forum Technology Pioneer—into a global leader advancing ACP-01, a patient-derived therapy proven to restore microcirculation, relieve ischemic pain, and prevent amputations in patients with critical limb ischemia (CLI) and peripheral arterial disease (PAD).

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Dr. Fraser Henderson

Chief Medical Officer

Dr. Fraser C. Henderson Sr. received his Bachelor’s and Medical degrees at the University of Virginia, Charlottesville, Virginia. He served in Beirut in 1983, completed a neurosurgery residency at the Medical University of South Carolina, then served as Neurosurgeon for the 4th Marine Expeditionary Brigade in the Gulf War in 1990-91. He was International Craniospinal Fellow at The National Hospitals for Neurology and Neurosurgery, Queen Square, London. Commander Henderson was then appointed Director of Neurosurgery of the Spine and Craniocervical Junction at Georgetown University. After promotion to Professor of Neurosurgery (Scholar tract) he entered private practice in 2008, remaining academically active as Director of The Metropolitan Neurosurgery Group in Maryland, and Adjunct Professor to University of Maryland . He has published 130 peer reviewed articles, patents and book chapters, co-edited five books, and given 200 invited lectures. 

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Dr. Mary Argent-Katwala, PhD

Manager, Clinical Trials

Over 20 years of leadership experience in the commercial, non-profit and government sectors. Strategic and systems thinker with track record of promoting optimal program performance through planning, collaboration, coaching and mentoring for quality and excellence. 

CL Bio_Pic for Website
Croom Lawrence

Chief Commercial Officer

Croom leads marketing, sales, patient services, and e-commerce for our pioneering angiogenic, autologous stem cell therapy, ACP-01.  Croom focuses his energy and passion to ensure ACP-01 and other life-changing treatments reach individuals who need them most.  Croom's career is defined by launching and scaling breakthrough therapies with over 25 years of experience in the biopharmaceutical sector and proven record of transforming single-product and large multinational franchise leaders into blockbuster successes. 

Board of Directors

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Peter Lacey, ICD.D

Chairman of the Board

Chairman of Cervus Equipment Corporation (CERV.TO), from inception to date.

President and Chief Executive Officer of Cervus Equipment Corporation and its predecessor entities from 1982 to April 2012.

Cervus is a company he and his partners started in 1999 and built from five John Deere dealerships to 63 dealerships selling six brands in three countries with revenues of $1.1 Billion.

Graduate of the Institute of Corporate Directors Education Program at the University of Toronto.

Hemostemix-Tom
Thomas A. Smeenk, BA

Director

A chief executive who structures, negotiates and has closed eight figure contracts. A dynamic business development and management team leader who delivers timely profitable results domestically and internationally. An adept communicator who succeeds at collaborative and interpersonal relationships with management, prospects, clients and suppliers.

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Dr. Ronnie Hershman, M.D., F.C.C.S.

Director

Graduated Magna Cum Laude from Sophie Davis Center for Biomedical Research in 1980.

Practicing Cardiologist since 1987 and Medical Director of NYU Langone Long island Cardiac Care.

Pioneer in performing laser assisted coronary angioplasty.

Entrepreneur and investor for more than two decades and director and/or officer of over 9 life science companies.

Track record of investing in companies that commercialize technologies quickly and globally.

Advisor to late stage life science VC that has funded 24 companies.

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Loran Swanberg

Director

Part owner and a director of a private company, Landsman Properties Ltd. since 2005. Landsman owns and leases out shop and office space in North East British Columbia and Alberta.

From 1992 to 2005, Mr. Swanberg was a director of the family owned oilfield transportation company, Swanberg Bros. Trucking Ltd., which was purchased by Producers Oilfield Services Inc. in 2005.

Director of privately held Swanberg Air Inc. from 2000 to 2012, and was a director of the Northern B.C. Truckers’ Association for 10 years, 1992 to 2002.

Most recently, Mr. Swanberg was a partner and director of Vieworx Geophoto Inc. from 2012 until Q1 2020.

Scientific Advisory Board

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Dr. Johannes Grilliari, PhD​

Dr. Grillari focuses on improving our understanding of the molecular and physiological changes that occur during cellular aging, their impact on organismal aging and tissue regeneration, specifically in skin and bone.

 

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Dr. Ernst von Schwarz, MD​

Considered a worldwide pioneer in the field of stem cell research, Dr. von Schwarz has published over 150 scientific papers in international peer reviewed medical journals, as well as books and book chapters in cardiovascular medicine.

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Dr. Norman Wong, MD​

Currently Professor of Medicine and Biochemistry & Molecular Biology and Director of the Libin Gene /Cell Therapy Unit within the Faculty of Medicine at the University of Calgary.

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Dr. Pierre Leimgruber, MD, FACC​

Board-certified in internal medicine, cardiovascular diseases, and interventional cardiology. Specialist in cardiovascular disease treatment.

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Dr. Alan Lumsden, MD​

International reputation as a leader in the field of endovascular surgery. He conducts FDA-mandated training for surgeons nationwide and has received millions of dollars for his research from the National Institutes of Health.

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Dr. Hari L. Kumar, PhD​

Expertise is in chromosome biology, functional genomics, and bioinformatics. Oversaw the development of the MRS and PATRN platforms.

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DR. INA SAREL

Dr. Ina Sarel is a biotechnology executive with more than 20 years of experience in product development from discovery and proof of concept through pre-clinical and clinical stages. Ina has broad expertise in stem/progenitor cell therapy, CMC, and regulatory requirements, and previously developed a stem cell research product commercialized by Lonza.

Some of Ina’s recent positions include VP Product Development at Cellect Biotechnology, VP R&D at Hemostemix, and Project Manager at Proneuron Biotechnologies.

Ina holds a Ph.D. in Neuroendocrinology from Boston University, USA.

DrHsiang
York N. Hsiang, MB. ChB., MHSc., FRCSC.

Professor Emeritus of Surgery and Former Head of Vascular Surgery at the University of British Columbia and Consultant Surgeon at the Vancouver General Hospital for 34 years. During that time, he treated thousands of patients, trained dozens of medical students to become doctors, and residents (medical graduates) to become surgeons. Born in Taiwan, educated in the United States, New Zealand, and Canada, Dr. Hsiang has diverse interests in vascular engineering, vascular biology, lasers, and clinical epidemiology. Dr. Hsiang has served as the Head of Vascular Surgery, UBC and Associate Head of Surgery, UBC. He was the Principal Investigator, Vancouver site, of the ACP-01 clinical trial for the application of angiogenic cell precursors for no option peripheral arterial disease patients. He has served as the Director of Surgical Research in the UBC Department of Surgery and has written over 120 scientific research articles plus a historical book on the development of vascular surgery at the Vancouver General Hospital, “Audible Bleeding”. He is a Distinguished Fellow of the Society for Vascular Surgery, the Past President of the Chinese Canadian Medical Society (BC), Pacific Northwest Vascular Surgery, and the Western Vascular Society.

 

 Request A Clinical Research Consultation 

 If you have been diagnosed with an advanced vascular or ischemic condition and are exploring investigational clinical research options, you may request a consultation to determine whether further review is appropriate. 

Disclaimer

IMPORTANT NOTICE
ACP-01 is an investigational therapy and has not been approved by the U.S. Food and Drug Administration. Information provided on this website is for educational purposes only and does not constitute medical advice. Nothing on this site is intended to promote or market an unapproved therapy. Patients should consult a qualified healthcare professional regarding diagnosis and treatment decisions.
 
FLORIDA NOTICE
This notice is provided in accordance with Florida law. One or more physicians referenced may perform stem cell therapies that have not been approved by the United States Food and Drug Administration. Patients are encouraged to consult with their primary care provider before undergoing any stem cell therapy.